The Magpies won 1-0 at Old Trafford on Saturday, compounding Everton's midweek victory, to leave the Red Devils languishing ninth in the Premier League.
His opposite number is battling to turn things around after taking over from legendary boss Sir Alex Ferguson in the summer and Pardew feels that the Scot has "already proven he's going to be great" for United.
"It's difficult for David and the club at the minute - they've had some tricky results," the Newcastle boss remarked to BBC Sport.
"He's a great manager. It's very important now that the fans of Manchester United and the board stick with him because he's already proven he's going to be great for this club but it is some sticky days; we all have them.
"David might need a year like that when it's touch-and-go but he'll get it right because he is a strong man," Pardew added. "I have a great respect for him.
"He had a bad break [on Saturday] with Wayne Rooney being unavailable because he'd been in top form."
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