The Gunners face the Partenopei in a crucial Champions League showdown on Wednesday and the former Chelsea boss has been impressed with the north Londoners' form this season.
The Spaniard feels that Arsenal are in with a great chance of lifting the Premier League trophy for the first time in 10 years but is still hopeful of leading Napoli to victory in a match that they must win by three clear goals in order to guarantee qualification for the last 16.
"This could be the year they win the league," Benitez told reporters. "For me Wenger is the best coach in the Premier League and knows what his team must do.
"Arsenal will try to control possession and hit us with counterattacks. We have to do our thing, focus on ourselves and not on them.
"In modern football everyone knows the quality of their rivals. Arsenal is a very strong side, we know, but we will try. My team have to give 100 per cent.
"My players know how important this game is and they have all trained really well. We have nothing to lose.
"For us, to play at home gives us an added strength. We were unlucky to be placed in such a difficult group but, for me, it's better to experience these games rather than watch them on TV."
